Description
Product Characteristics: Purified recombinant Mouse Mouse BLC + BCA 1 protein
Expression System: E.coli
Bioactivity: Determined by its ability to chemoattract Mouse B cells using a concentration of 10.0-100.0 ng/mL.
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Target Information: B lymphocyte chemoattractant, independently cloned and named Angie, is a CXC chemokine strongly expressed in the follicles of the spleen, lymph nodes, and Peyer's patches. It preferentially promotes the migration of B lymphocytes (compared to T cells and macrophages), apparently by stimulating calcium influx into, and chemotaxis of, cells expressing Burkitt's lymphoma receptor 1 (BLR-1). It may therefore function in the homing of B lymphocytes to follicles. [provided by RefSeq, Jul 2008]